Retatrutide is a medication designed primarily for weight management. It works by targeting certain receptors in the body to help control hunger and appetite, thereby aiding in weight loss.
VLS RETATRUTIDE
for Weightloss
Increased appetite suppression
Retatrutide can help regulate insulin secretion and improve insulin sensitivity
Improved metabolic health
Improved long term weight management
FAQs
Q: What is VLS Retatrutide?
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Retatrutide (VLS brand) is used for weight loss, to help lose weight and keep weight off, Retatrutide is a combination of three different hormones:
1. GLP-1 (glucagon-like peptide-1): This hormone helps regulate blood sugar levels and reduces appetite.
2. GIP (gastric inhibitory polypeptide): It plays a role in insulin secretion and may help reduce appetite.
3. Glucagon: It helps regulate blood sugar and energy balance in the body.
By combining these hormones, retatrutide aims to help individuals lose weight by making them feel full with smaller amounts of food and reducing the desire to eat.
Q: When should I not use VLS Retatrutide?
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Do not use VLS Retatrutide if:
• Risk of Thyroid Tumors: Like other GLP-1 receptor agonists, retatrutide could increase the risk of developing thyroid tumors, including medullary thyroid cancer. People with a family history of MTC or MEN 2 are generally advised not to use drugs in this class.
• Gastrointestinal Side Effects: Retatrutide, like other similar medications, may cause gastrointestinal side effects such as nausea, vomiting, diarrhea, or constipation. Those with severe gastrointestinal conditions (e.g., gastroparesis, bowel obstruction) might experience worsened symptoms or complications.
• Risk of Hypoglycemia: While retatrutide has shown potential for controlling blood sugar in Type 2 diabetes, it is not intended for use in Type 1 diabetes. The medication may cause blood sugar to drop too low in people with Type 1 diabetes, potentially leading to dangerous hypoglycemic episodes.
Q: How should I use VLS Retatrutide?
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Use VLS Retatrutide exactly as your healthcare provider tells
you to.
• VLS Retatrutide is injected under the skin (subcutaneously)
of your stomach (abdomen), thigh, or upper arm. Do not inject
VLS Retatrutide into a muscle (intramuscularly) or vein
(intravenously).
• Use VLS Retatrutide 1 time each week, on the same day each
week, at any time of the day.
• You may change the day of the week you use VLS Retatrutide
as long as your last dose was given 2 or more days before.
• If you miss a dose of VLS Retatrutide, take the missed dose
as soon as possible within 5 days after the missed dose. If
more than 5 days have passed, skip the missed dose and take
your next dose on the regularly scheduled day.
• VLS Retatrutide may be taken with or without food.
• Do not mix insulin and VLS Retatrutide together in the same
injection.
• You may give an injection of VLS Retatrutide and insulin in
the same body area (such as your stomach area), but not right
next to each other.
• Change (rotate) your injection site with each injection. Do
not use the same site for each injection.
• Check your blood sugar as your healthcare provider tells you
to.
• Stay on your prescribed diet and exercise program while
using VLS Retatrutide.
• Talk to your healthcare provider about how to prevent,
recognize and manage low blood sugar(hypoglycemia), high blood
sugar (hyperglycemia), and problems you have because of your
diabetes.
• Your healthcare provider will check your diabetes with
regular blood tests, including your blood sugar levels and
your hemoglobin A1C.
• Do not share your VLS Retatrutide pen with other people,
even if the needle has been changed. You may give other people
a serious infection, or get a serious infection from them.
• Your dose of VLS Retatrutide and other diabetes medicines
may need to change because of change in level of physical
activity or exercise, weight gain or loss, increased stress,
illness, change in diet, fever, trauma, infection, surgery or
because of other medicines you take.
• If you take too much VLS Retatrutide, call your healthcare
provider or go to the nearest hospital emergency room right
away.
Q: What are the possible side effects of VLS Retatrutide?
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Common Side Effects:
1. Gastrointestinal Issues:
○ Nausea:
A common side effect, especially when starting the medication. This tends to improve over time as the body adjusts.
○ Vomiting:
Some people may experience vomiting, particularly during the initial stages of treatment.
○ Diarrhea or Constipation:
These can occur, with some people experiencing one more than the other.
○ Abdominal Pain:
Stomach discomfort or pain is also reported by some users.
2. These gastrointestinal side effects tend to be temporary but can be bothersome for some people. Doctors often recommend starting with a lower dose and gradually increasing to help minimize these symptoms.
3. Decreased Appetite
○ While this is a desired effect for many, some people may experience it too strongly, leading to reduced food intake and potential issues like fatigue or weakness.
○ Potential Risk:
Similar to other GLP-1 receptor agonists, retatrutide may carry a risk of thyroid tumors, including medullary thyroid cancer (MTC), and a possible increased risk of developing certain types of thyroid conditions.
○ Caution for those with a Family History:
It is especially not recommended for people with a family history of MTC or multiple endocrine neoplasia syndrome type 2 (MEN 2).
2. Pancreatitis (Inflammation of the Pancreas):
○ Symptoms:
Severe abdominal pain, nausea, and vomiting could indicate pancreatitis. If this happens, the drug should be discontinued immediately, and medical attention sought.
3. Kidney Problems:
○ Dehydration Risk:
If nausea, vomiting, or diarrhea are severe, dehydration could occur, which may lead to kidney problems. People with preexisting kidney conditions may need to be more cautious.
4. Low Blood Sugar (Hypoglycemia):
○ This is more likely to occur if Retatrutide is used in combination with other diabetes medications that lower blood sugar, such as insulin or sulfonylureas.
○ Symptoms:
Shaking, sweating, dizziness, and confusion are signs of low blood sugar.
5. Allergic Reactions:
○ Symptoms:
Rash, itching, swelling, or difficulty breathing could indicate an allergic reaction. In severe cases, this could lead to anaphylaxis (a life-threatening reaction), though this is rare.
6. Gallbladder Problems:
○ Gallstones:
There is a potential risk of developing gallstones, which could lead to pain in the upper abdomen, nausea, and vomiting.
Usage
Initial Dose Escalation Schedule
Weeks 1 through 4: 2 mg subcutaneously once a
week
Weeks 5 through 8: 5 mg subcutaneously once a
week
Weeks 9 through 12: 8 mg subcutaneously once a
week
Weeks 13 through 16: 10 mg subcutaneously once a
week
Maintenance Dose
Week 17 and onward: 2.5 mg subcutaneously once a
week
Dosing Considerations
If dose escalation is not tolerated, consider delaying dose escalation for 4 weeks
Do not increase dose if desired results are achieved at a lower dose, most people maintain at 10mg per week
Instructions
Step 1:
1. Wash your hands with soap and water.
2. Check the name and
colored label of your
pen, to make sure that it
contains VLS Retatrutide.
This is especially
important if you take
more than 1 type of
medicine.
3. Pull off the pen cap.
Step 2:
1. Check that the VLS Retatrutide medicine in your pen is clear and colorless. Look through the pen
window. If VLS Retatrutide
looks cloudy or contains
particles, do not use the
pen.
Step 3:
1. Take a new needle,
and tear off the paper tab.
2. Do not attach a new
needle to your pen until
you are ready to give your
injection.
Step 4:
1. Push the needle
straight onto the pen.
Turn until it is on
tight.
Step 5:
1. The needle is covered
by 2 caps. You must
remove both caps. If
you forget to remove both
caps, you will not inject
any medicine.
2. Pull off the outer
needle cap. Do not
throw it away.
Step 6:
1. Pull off the inner
needle cap and throw
it away.
Step 7:
1. Check the VLS Retatrutide
flow before the first
injection with each
new pen only.
2. Turn the dose selector
until the dose counter
shows the flow check symbol ▪▪▰
Step 8:
1. Hold the pen with the
needle pointing up.
Press and hold in the
dose button until the
dose counter shows 0.
The 0 must line up with
the dose pointer.
A drop of VLS Retatrutide will
appear at the needle tip.
2. If no drop appears,
repeat Step 7 above as
shown in Figure G and
Figure H up to 6 times.
3. If there is still no drop,
change the needle and
repeat Step 7 as shown
in Figure G and Figure H,
1 more time.
Do not use the pen if
a drop of VLS Retatrutide still
does not appear.
Contact at vls-pen@protonmail.com.
Step 9:
Select your dose
1. Turn the dose selector
until the dose counter
stops and shows your
2 mg dose.
The dashed line in the
dose counter (┇) will
guide you to 2 mg.
2. Always use the dose counter and the dose pointer to
see that 2 mg has been selected.
You will hear a “click” every time you turn the dose selector.
Do not set the dose by counting the number of clicks
you hear.
Only doses of 2 mg can be selected with the dose
selector.
Step 10:
To see how much VLS Retatrutide is left in your pen, use the dose counter:
1. Turn the dose selector
until the dose counter
stops.
2. If it shows 1, at
least 1 mg is left
in your pen. If the
dose counter stops
before 1 mg,
there is not enough
VLS Retatrutide left for a
full dose of 1 mg.
If there is not enough VLS Retatrutide left in your pen for a
full dose, do not use it. Use a new VLS Retatrutide pen.
Step 11:
Inject your dose
1. Choose your injection
site and wipe the skin
with an alcohol swab.
Let the injection site dry
before you inject your
dose (See Figure K).
Step 12:
1. Insert the needle
into your skin as your
healthcare provider has
shown you.
2. Make sure you can
see the dose counter.
Do not cover it with your
fingers. This could stop
the injection.
Step 13:
1. Press and hold down
the dose button until
the dose counter
shows 0.
2. The 0 must line up with
the dose pointer. You may
then hear or feel a click.
3. Continue pressing
the dose button while
keeping the needle in
your skin.
Step 14:
1. Count 6 seconds
while keeping the
dose button pressed.
2. If the needle is removed
earlier, you may see a
stream of VLS Retatrutide
coming from the needle
tip. If this happens, the
full dose will not be
delivered.
Step 15:
1. Remove the needle
from your skin. You
can then release the dose
button.
2. If blood appears at the
injection site, press
lightly with a gauze pad
or cotton ball.
Do not rub
the area.
Step 16:
After your injection
1. Carefully remove the
needle from the pen.
Do not put the needle
caps back on the needle
to avoid needle sticks.
Step 17:
1. Place the needle in
a sharps disposal
container right away to
reduce the risk of needle
sticks.
Step 18:
1. Put the pen cap on
your pen after each use to
protect VLS Retatrutide from
light.
Step 19:
1. If you do not have a
sharps disposal container,
follow a 1-handed needle
recapping method.
Carefully slip the needle
into the outer needle cap.
Dispose of the needle in a
sharps disposal container
as soon as possible.
2. Never try to put the inner needle cap back on the needle. Always remove the needle from your pen.
3. Always dispose of the needle after each injection.
